Lignans with Anticancer Activity : Lignanların Antikanser Etkileri
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چکیده
منابع مشابه
In vitro anticancer and antioxidant activity studies on Drosera peltata J.E.Sm. Drosera peltata J.E.Sm.’in in vitro antikanser ve antioksidan aktivitesi
Aim:The present study aimed to assess the in vitro antioxidant and anticancer properties of Drosera peltata J.E.Sm. Methods:Antioxidant capacity of the extracts were tested on hydroxyl, DPPH, super oxide, nitric oxide and ABTS radicals; of ferrous ion chelating ability and by reducing power assay.Ascorbic acid was used as the standard antioxidant for the above all assay methods. Dalton’s Asciti...
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Anthriscus sylvestris (L.) Hoffm. is a wild herbaceous plant common in most temperate regions. It has been used traditionally to treat headaches, as a tonic, as antitussive, antipyretic, analgesic and diuretic. The plant contains deoxypodophyllotoxin, which is proven to have antitumor and anti-proliferative effects, anti-platelet aggregation, antiviral, anti-inflammatory and insecticidal activi...
متن کاملInvestigation of Linum flavum (L.) Hairy Root Cultures for the Production of Anticancer Aryltetralin Lignans.
Linum flavum hairy root lines were established from hypocotyl pieces using Agrobacterium rhizogenes strains LBA 9402 and ATCC 15834. Both strains were effective for transformation but induction of hairy root phenotype was more stable with strain ATCC 15834. Whereas similar accumulation patterns were observed in podophyllotoxin-related compounds (6-methoxy-podophyllotoxin, podophyllotoxin and de...
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Extracts from Holostylis reniformis were tested in vivo against Plasmodium berghei and in vitro against a chloroquine-resistant strain of Plasmodium falciparum. The hexane extract of the roots was the most active, causing 67% reduction of parasitemia in vivo. From this extract, six lignans, including a new (7'R,8S,8'S)-3',4'-methylenedioxy-4,5-dimethoxy-2,7'-cyclolignan-7-one, were isolated and...
متن کاملAntileukemic activity of lignans and phenylpropanoids of Cinnamomum parthenoxylon.
In this study, we evaluated the in vitro cytotoxicity of fractions and isolated constituents from Cinnamomum parthenoxylon woods against human leukemia HL-60 and U937 cells. The n-Hex, EtOAc, and MeOH-H2O fractions of the woods inhibited cell proliferation in both cell lines. Our phytochemical investigation of the n-Hex and EtOAc fractions led to the isolation of lignans and phenylpropanoids, w...
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ژورنال
عنوان ژورنال: Ankara Universitesi Eczacilik Fakultesi Dergisi
سال: 1995
ISSN: 1015-3918
DOI: 10.1501/eczfak_0000000444